New post on another blog: Radiance
I found the above article interesting as the chemical constituents in marijuana are very healing, when used topically, for many skin conditions. As someone who has mild, and yet very irritating psoriasis on knees and elbows, this could be useful information.
I have found that eating a wheat free diet and more specifically, a gluten free diet, my dear friend, psoriasis, lies very low over the winter. The sun, shining brightly in summer, keeps it mellow!
There is information all over the internet on cannabis creams healing psoriasis, eczema, acne, and other skin conditions.
Cannabinoids as Treatment for Psoriasis Symptoms
Research: Cannabinoids inhibit keratinocyte proliferation, and therefore support a potential role for cannabinoids in the treatment of psoriasis. Cannabis might treat psoriasis, due to the anti-inflammatory properties of its cannabinoids, and the regulatory effects of THC on the immune system. The adverse effects of cannabis might be overcome by use of more specific cannabinoid receptor medications, to inhibit keratinocyte proliferation. Moreover, they observe that cannabinoids are readily absorbed through the skin. This is the ideal method of treating psoriasis, as it avoids some of the toxicity associated with systemic therapies. The researchers tested the effects of four plant cannabinoids – Δ-9 tetrahydrocannabinol, cannabidiol, cannabinol and cannabigerol – on rapidly proliferating, cultured human keratinocytes. All four cannabinoids inhibited keratinocyte growth in a dose-dependent manner, they report. Despite varying degrees of affinity for cannabinoid receptors (CBs) among the substances tested, the extent of growth inhibition was similar with all four cannabinoids, implying a non-specific effect. In confirmation of this, the investigators found that selective CB2 agonists only partially inhibited keratinocyte growth, while a non-selective CB agonist had a concentration-dependent effect. Neither CB1 nor CB2 antagonists attenuated the effects of the CB agonists or the cannabinoids, however. Furthermore, these antagonists actually exhibited direct dose-dependent inhibition of keratinocyte growth. Cannabinoids, as novel additions to the anti-psoriatic ammunition. Source: Dermatology Department, Shiraz University of Medical Sciences, Shiraz, Iran. firstname.lastname@example.org cannabinoids, which exert inhibitory effects on antigen processing and macrophage/T-cell interaction and on the release of IL-2, TNF-alpha and nitric oxide from immune cells. Testimonials: Cannabinoids extracted with grape seed oil: can be taken orally or topically applied or both. ““HempEase” made from cannabis roots (no THC) has powerful skin treating qualities”. Cannabinoids can be taken orally, and applied topically for the treatment of psoriasis symptoms with little to no side effects.